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Our advances address some of the biggest challenges in neuroscience


The ‘in conversation’ series features members of the Wyss Center community discussing their work, their collaborations and imagining the future.


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Discovering new sub-cellular worlds in 3D brain samples

3D spatial transcriptomics may hold clues to future therapies for brain diseases. The technique measures gene expression from the RNA found in cells. It tells us what type of cell it is, exactly where it is, and can also indicate how a cell may interact with neighboring structures to the sides, above or below.

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Completely locked-in man uses brain-computer interface to communicate

The system, developed for people with complete locked-in syndrome, allows communication over periods of months to years, in the home environment. It paves the way for new technologies for people with severe paralysis.

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Revealing 3D anatomy with lightsheet microscopy

Developers around the world are pushing microscope technology to the extremes. Lightsheet microscopes image brain tissue down to individual neurons and offer unprecedented maps of nervous system structure and function.