Wyss Center partners with Coat-X to advance ultra-thin coating for use in active medical implants

The Wyss Center’s custom-built accelerated aging system verifies the long-term performance of implantable devices in the human body

The flexible coating technology could pave the way for miniaturized devices in the human body


GENEVA & LA CHAUX-DE-FONDS, SWITZERLAND – Active implants, such as cardiac pacemakers, cochlear implants and neural monitoring or stimulation devices, contain sensitive electronics that must be protected from the warm, wet, and salty environment of the human body. As a result, conventional hermetic housings are composed of titanium, glass, or ceramic, and are made thick and rigid to ensure that devices in the body are leakproof and can survive for years.

The Wyss Center for Bio and Neuroengineering and the Swiss technology company Coat-X today announced a collaboration to bring to market a new ultra-thin, biocompatible coating for use in active medical implants. At only ten microns thick, the flexible coating conforms to the shape of the electronics, encasing them directly in a leakproof, biocompatible envelope.

George Kouvas, MBA, Chief Technology Officer at the Wyss Center said: “Despite advances in the microfabrication of electronics, active implants today still have relatively large volumes. This is mainly due to the limited scalability of traditional medical implant housing technologies. The electronics may shrink but this is not the case for their housings. Our partnership with Coat-X will validate the use of a new, thin-film coating technology, paving the way for the miniaturization of medical implants and enabling a future where very small medical devices are seamlessly integrated with the human body.”

The collaboration will bring materials engineers from Coat-X together with the Wyss Center’s electromechanical team. “We will apply Coat-X’s multilayer encapsulation technology in active medical implants, such as next generation electrodes and electronics,” said Andreas Hogg, CEO at Coat-X. “We will start by using a custom-built accelerated aging system at the Wyss Center to verify the long-term performance of our coating technology in the human body,” he added.

The team will develop and coat prototype devices with several variations of the encapsulation technology and then will subject them to high temperatures and humidity to accelerate their aging. Electronic tags built into the devices will wirelessly send updates on the internal status of the electronics, continuously assessing the hermeticity of the new coating and giving valuable information on its performance and reliability in the body.

“If we can validate that Coat-X’s ultra-thin coating has favorable barrier and durability properties in the long term, we will further our collaboration to bring this technology to market and, hopefully, enable even smaller medical devices to be implanted in patients around the world,” added Wyss Center’s CEO Mary Tolikas, Ph.D., MBA.

Coat-X established a 13485 certified coating center in an ISO5 cleanroom equipped with 3 coating reactors. Credit: Coat-X

Related to

An implantable brain-computer interface (BCI) to restore movement and communication
Helping entrepreneurs accelerate their journey from bench to market
Long-term brain monitoring and therapeutics for personalized management of neuro-disorders
Combining neuroscience, advanced engineering and manufacturing
Advanced electrical and mechanical engineering design and fabrication

Prototyping laboratories

Advanced electrical and mechanical engineering design and fabrication

The ‘in conversation’ series features members of the Wyss Center community discussing their work, their collaborations and imagining the future.


Translating arm and hand movement intentions into action
Wyss Center


A new model of cooperation and collaboration to accelerate translational research and development in the field of neurotechnology and artificial intelligence.