Mackenzie Mathis is the Bertarelli Foundation Chair of Integrative Neuroscience at the Swiss Federal Institute of Technology, Lausanne (EPFL). She is an assistant professor within the Brain Mind Institute, Center for Neuroprosthetics, and Center for Intelligent Systems at EPFL, as well as an EPFL ELLIS Unit Faculty Member, having joined EPFL in 2020 after moving her lab from Harvard University where she held the Rowland Fellowship.

She is also an ELLIS Scholar and elected member of the Natural Intelligence ELLIS Program.

Her lab works on mechanisms underlying adaptive behavior in intelligent systems. Specifically, the laboratory combines machine learning, computer vision, and experimental work in rodents with the combined goal of understanding the neural basis of adaptive motor control, which may lead to new avenues in therapeutic research for neurological disease.