Non-Invasive DBS for neuropsychiatric disorders
Leveraging AI to enable precision treatments of mental diseases

Goal | Neuromodulation of mental health area in the brain
Status | ongoing
Timeframe | 2024 – 2027
Area of Research | AI-guided neuromodulation
Partners | HUG, EPFL, CHUV, UNIGE, FCBG
Affiliation | This project is part of the Lighthouse Partnership
Leveraging AI to enable precision treatments of mental diseases (Non-invasive DBS)
This research project develops non-invasive DBS as a novel, disruptive treatment strategy for a range of neuropsychiatric disorders. It targets symptom-specific circuits, focusing on apathy, memory deficits, and compulsion that are observed in several neurologic and psychiatric disorders, including but not limited to Parkinson’s disease, MCI, addiction, OCD, depression, and schizophrenia.
Our team addresses several unique key concepts including new non-invasive technologies for deep brain stimulation, deep phenotyping, and personalized and AI-guided neuromodulation.

The Lighthouse Partnership
This project is part of the Lighthouse Partnership, an inter-institutional collaboration bringing together scientists, engineers, and clinicians with the goal of accelerating AI-guided neuromodulation. By harnessing the interdisciplinary expertise present in the Lemanic Region, the Lighthouse Partnership addresses the increasing global challenge of neurological and mental health disorders with leading institutions.