Stéphane Pagès, PhD

Director of Neuroimaging

Stéphane's expertise in innovative optical approaches is instrumental in the continued development and customization of the Wyss Center's advanced imaging facility.

Stéphane joined the Wyss Center in 2016 and became Director of Neuroimaging in 2021. He is also an Academic Fellow of the University of Geneva, in the Department of Fundamental Neurosciences.

Stéphane oversaw the setting up of an advanced imaging facility at the Wyss Center based on innovative optical approaches. The first microscope that he built was a Clarity Optimized Lightsheet Microscope (COLM) for whole brain imaging at subcellular resolution. This was followed by the construction of a mesoscale Single Plane Illumination Microscope (mesoSPIM – mesoSPIM.org). Finally, he contributed to the emergence of the Advanced Light Sheet Imaging Center (ALICe), an entire pipeline dedicated to clarification and high-resolution imaging of tissue.

After his PhD in ultrafast spectroscopy and non-linear optics at the UNIGE Science Department, he joined the Neurophotonics Center at Laval University, Canada as a FNS postdoctoral fellow where he developed new optical approaches to optically record membrane potential changes and calcium dynamics in dendritic spines.

He also participated in the development of an autofocus device for two-photon microscopes to image calcium dynamics in the spinal cord of living rodents. In 2011, he joined the Anthony Holtmaat’s team at UNIGE to pursue his research on neuronal functional and structural plasticity in vivo.

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Contributing to

Advancing our understanding of the brain's complex circuitry
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Expertise
State-of-the-art advanced lightsheet imaging center
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Facility
A new view of glioblastoma could help predict patient outcomes
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Advance
Training AI models to identify neurons across the brain
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Advance
Brain mapping: Uniting multi-scale brain data to reveal disease mechanisms
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Advance
Exploring the gut-brain connection in the quest to solve brain disorders
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Advance
Translational project will create the first detailed 3D maps of human glioblastomas with an integrated ‘tissue time machine’ to predict response to therapies.
Collaboration

08.10.2021

The results could help clinicians understand addiction and enable people to better manage substance withdrawal.
Collaboration

31.03.2021

Revealing details of the internal structure of ‘mini-brains’ could help accelerate drug studies and may offer alternatives to some animal testing.
Collaboration

07.01.2021

Researchers around the world share their stunning images and insights: The open source mesoSPIM Initiative.
Collaboration

16.09.2019

Collaboration

19.03.2018

Team

Steven Ceto

Steven Ceto, BS, PhD

Senior Research Scientist
Bertrand Gabry

Bertrand Gabry, MSc, PhD

V&V Manager
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Maxim Andersen, MSc

Software Engineer in Neuroengineering Applications
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Mark A. Anderson, PhD

Research Scientist - Head of Spinal Cord Repair
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Tiago Bertolote, MSc

Mechanical Engineer
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Florent Burdin, MEng

Electronics Systems Engineer for Implantable Medical Devices
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Thierry Campiche

Software Engineer in Neuroengineering
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Etienne de Montalivet

Machine Learning Scientist
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Joachim Dunant, MSc

Neuroengineer for Brain-Computer-Interface Project
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Arnau Espinosa, MSc

Senior Engineering Manager
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Gary Evans, BSc

R&D Mechanical Engineer
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Hugo França, PhD

R&D Electrical Engineer Manager
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Jérôme Gandar, PhD

Project Manager – VascuSAFE Project
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Sriparna Ghosal, PhD

Research Scientist in CNS Therapy
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Michalina Gora, PhD

Manager in Neurophotonics
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Arnaud Herbert, MSc

Wireless Systems Electrical Engineer
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Clémence Hurni, PhD

Staff Scientist in 3D Transcriptomics
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Tom Hutson, PhD

Group Leader
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Selen Keles, MSc

Project Leader/Neuro Engineer for BCI
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Toko Kikuchi, PhD

Research Scientist
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Matthew Lapinski, MSE

Mechanical Engineering Manager
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Kyuhwa Lee, PhD

NeuroAI Group Leader
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Pablo Maceira Elvira, PhD

Neuroengineer
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Jérémie Martin, MSc

Junior Software Engineer
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Sébastien Menot, MSc

R&D Mechanical Engineer
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Nima Mojtahedi, PhD

Machine Learning Scientist
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Shenandoah Montamat, MSc

Operations Manager
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Samira Osterop, MSc

Neurobiology Research Associate
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Arielle Planchette, PhD

Research Scientist
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Sébastien Pernecker, MSc

Embedded Software Engineer
Frédéric

Frédéric Pittet

Embedded Software Engineer
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Denis Rambaud, MSc

Electronics Engineer for MedTech Devices
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Janir Ramos da Cruz, PhD

Data Scientist
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Jules Scholler, PhD

Photonics and Software Engineer
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Aleksander Sobolewski, PhD

Staff Neuroscientist
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David Ibáñez Soria, PhD

Senior Engineering Manager / Brain-Machine Interface (BMI) Scientist
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Andrea Volterra, PhD

Visiting Faculty
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Karol Wojcicki, BSc

Engineering Lab Technician
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Ioannis Zalachoras, PhD

Research Project Manager
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Jonas Zimmermann, PhD

Senior Project Lead - Senior Neuroscientist